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In addition, antipsychotic drug treatment has been associated with swallowing and breathing problems in older people and those with Alzheimer's disease.Drugs such as Zyprexa sometimes cause a condition called Neuroleptic Malignant Syndrome (NMS). Symptoms include high fever, muscle rigidity, irregular pulse or blood pressure, rapid heartbeat, excessive sweating, and changes in heart rhythm. If these symptoms appear, contact your doctor right away. You'll have to discontinue using Zyprexa while the condition is under treatment.There is also a risk of developing tardive dyskinesia, a condition marked by slow, rhythmical, involuntary movements. This problem is more likely to surface in older adults, especially elderly women.

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Zyprexa Precautions

This increase is likely due to the fact that carbamazepine is a potent inducer of CYP1A2 activity. Higher daily doses of carbamazepine may cause an even greater increase in olanzapine clearance. -- Ethanol (45 mg/70 kg single dose) did not have an effect on olanzapine pharmacokinetics. -- Fluoxetine (60 mg single dose or 60 mg daily for 8 days) causes a small (mean 16%) increase in the maximum concentration of olanzapine and a small (mean 16%) decrease in olanzapine clearance.

Zyprexa Uses

This medication is used to treat certain mental/mood conditions (schizophrenia, bipolar mania). It works by helping to restore the balance of certain natural chemicals in the brain (neurotransmitters). Take as directed, usually once a day by mouth with or without food. Canadian residents should call their local poison control center directly. Parturition in rats was not affected by olanzapine. It is not known if olanzapine is excreted in human milk. The following findings are based on premarketing trials of (1) oral olanzapine for schizophrenia, bipolar mania, a subsequent trial of patients having various psychiatric symptoms in association with Alzheimer's disease, and premarketing combination trials, and (2) intramuscular olanzapine for injection in agitated patients with schizophrenia or bipolar mania.

How To Use Zyprexa Oral

The incidence of mammary gland adenomas and adenocarcinomas was significantly increased in female mice dosed at /=2 mg/kg/day and in female rats dosed at /=4 mg/kg/day (0.5 and 2 times the maximum recommended human daily oral dose on a mg/m basis, respectively). Antipsychotic drugs have been shown to chronically elevate prolactin levels in rodents. There may be a slightly increased risk of serious, possibly fatal side effects (e.g., stroke, heart failure) when this medication is used in elderly patients with dementia.

Zyprexa Overdose

Stand up slowly, especially when starting this medication, to avoid dizziness. The dosage is based on your medical condition and response to therapy. Use this medication regularly in order to get the most benefit from it. -- In oral reproduction studies in rats at doses up to 18 mg/kg/day and in rabbits at doses up to 30 mg/kg/day (9 and 30 times the maximum recommended human daily oral dose on a mg/m basis, respectively) no evidence of teratogenicity was observed.

Zyprexa Missed Dose

Remember to use it at the same time each day. There are no adequate and well-controlled trials with olanzapine in pregnant females. The prescriber should be aware that the figures in the tables and tabulations cannot be used to predict the incidence of side effects in the course of usual medical practice where patient characteristics and other factors differ from those that prevailed in the clinical trials. Similarly, the cited frequencies cannot be compared with figures obtained from other clinical investigations involving different treatments, uses, and investigators.